Kassis is a surname. Notable people with the surname include:
Kyriakos D. Kassis (1946–2025), Greek poet and painter Nabeel Kassis (born 1945), Palestinian academic and politician Nick Kassis (born 1988), Lebanese rugby league footballer Randa Kassis (born 1970), Franco-Syrian politician Reem Kassis (born 1987), Palestinian writer and author
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