A list of examples of in vivo transdifferentiation through transfection: mouse hepatocytes → B cells (Pdx1) exocrine cells → B cells (Pdx1, Ngn3, and v-maf musculoaponeurotic fibrosarcoma oncogene family protein A) nonsensory cells → inner hair cells (Atoh1 and MathI) non cardiogenic mesoderm → cardiomyocytes (Gata4, Tbx5 and Smarcd3 or Baf60c)
Through excision: B-cell precursors → hematopoietic progenitors(-Pax5) In adult ovarian follicles, granulosa and thecal cells → functional Sertoli-like and Leydig-like cells (-Foxl1)
See also Transdifferentiation Induced stem cells
References