René Deffke (born 9 November 1966) is a German football manager and former player. He is currently the manager of BV Bad Lippspringe.
Early in his career, Deffke played one season in the East German Oberliga for 1. FC Union Berlin. After the German reunification, he went on to play eight seasons in the 2. Bundesliga, before playing mostly in the third tier of German football until he retired from the game in 2000.
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