Comolli is a surname. Notable people with the surname include:
Damien Comolli (born 1971), French football coach, scout and director Giovanni Battista Comolli (1775–1831), Italian sculptor Jean-Louis Comolli (1941–2022), French writer, editor, and film director Jessica Comolli (born 1985), beauty queen from Montpelier, Vermont
See also Comollo (surname)