Amphlett is a surname. Notable people with the surname include:
Christina Amphlett (1959–2013), the lead singer of Australian rock band Divinyls Edgar Amphlett (1867–1931), British fencer and journalist Patricia Amphlett (born 1949), Australian singer whose stage name was Little Pattie Richard Amphlett (1809–1883), English barrister and Conservative politician Tommy Amphlett (born 1988), English-born association football player
See also Amphilestes Neauphlette