Polyphemus is a Cyclops in Greek mythology.

Polyphemus may also refer to:

Animals Antheraea polyphemus, or Polyphemus moth, a giant silk moth of North America Polyphemus (crustacean), a genus of cladocerans Limulus polyphemus, the Atlantic horseshoe crab Mecynorhina polyphemus, a species of beetle Art and entertainment Polyphemus (book), a collection of short stories by Michael Shea Polyphemus (Reni), a 1639–1640 painting by Guido Reni Polyphemus (sculpture), an 1888 bronze by Auguste Rodin Polifemo (1735), an Italian opera by Nicola Porpora Polyphème (1922), a French opera by Jean Cras based on a 1902 verse play by Albert Samain The name of the gas giant in the Avatar series, which Pandora orbits

Other uses Polyphemus (Argonaut), another figure from Greek mythology HMS Polyphemus, the name of several ships of the British Royal Navy

See also

Polifemo, a 1627 poem by Luis de Góngora y Argote Polyphem (missile), a cancelled surface-to-surface missile project Polyphemus#Possible origins, for folktales similar to that of Homer's Polyphemus