Samudio may refer to:
Álvaro Cepeda Samudio (1926–1972), Colombian journalist, novelist, short story writer, and filmmaker Braian Samudio (born 1995), Paraguayan football player Bruninho Samudio (born 2010), Brazilian professional goalkeeper Domingo "Sam" Samudio or "Sam the Sham" (born 1937), stage name of American rock and roll singer Domingo "Sam" Zamudio Eliza Samudio (1985–2010), Brazilian model Juan Samudio (born 1978), Paraguayan footballer Miguel Samudio (born 1986), Paraguayan footballer Nicholas Samudio, man with Down syndrome accused by police of being a hitman for the Latin Kings Patrocinio Samudio (1975–2017), Paraguayan footballer
See also Samuda Zamudio Zamudio SD