The Sicydiinae are a small subfamily (about 118 species) of freshwater gobies, with only nine genera. They are usually found in fast-moving mountain streams in tropical islands. They are characterized by highly developed rounded suction discs and an amphidromous lifecycle. Adult lengths range from . Some species are popular in the aquarium trade. The genera included under Sicydiinae are:

Akihito Watson, Keith, and Marquet, 2007 Cotylopus Guichenot, 1863 Lentipes Günther, 1861 Parasicydium Risch, 1980 Sicyopterus Gill, 1860 Sicyopus Gill, 1863 Smilosicyopus Watson, 1999 Stiphodon Weber, 1895 Sicydium Cuvier & Valenciennes, 1837

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