Wye Bridge is a section of the Severn Bridge, the first road bridge built over the Severn Estuary which now carries the M48 motorway.

Wye Bridge may also refer:

Bridges across the River Wye Old Wye Bridge, Chepstow Wye Bridge, Hereford, a Grade I listed bridge in Herefordshire Wye Bridge, Monmouth

Bridges elsewhere a bridge in Wye, Kent

See also List of crossings of the River Wye