Vicario is a surname. Notable people with the surname include:
Enzo Vicario (born 1942), Italian bobsledder Guglielmo Vicario (born 1996), Italian footballer Jaron Vicario (born 1999), Italian footballer Leona Vicario (1789–1842), Mexican revolutionary Marco Vicario (1925–2020), Italian film actor, screenwriter, producer and director Margherita Vicario (born 1988), Italian singer, songwriter and actress
See also Arantxa Sánchez Vicario, Spanish tennis player El Vicario, winery in Spain