Clyburn is a surname. Notable people with the surname include:
Bill Clyburn (born 1941), American politician from South Carolina Danny Clyburn (1974–2012), American baseball player Jennifer Clyburn Reed, American businessperson and schoolteacher, a daughter of Jim Clyburn Jim Clyburn (born 1940), American politician and former Majority Whip in the U.S. House of Representatives Kris Clyburn (born 1996), American basketball player for Maccabi Rishon LeZion of the Israeli Basketball Premier League Mattie Clyburn (1922–2014), African-American member of the United Daughters of the Confederacy Mignon Clyburn (born 1962), American bureaucrat Weary Clyburn (1841–1930), American slave Will Clyburn (born 1990), professional basketball player, 2016 top scorer in the Israel Basketball Premier League, 2019 EuroLeague Final Four MVP
See also Clyburn Lake, Canadian lake Clyburn railway station, Australian railroad station