SQ1 may refer to:
Space Quest I, a 1986 video game SQ1, a galactic quadrant in the Milky Way SQ1, a mixtape by Lil Wayne SQ1, a Singapore Airlines flight that flies from Hong Kong to Singapore in the morning, and from San Francisco at night. Microsoft SQ1, a system on a chip sq1, a common abbreviation for the Square-1 (puzzle)
See also SQL, special-purpose programming language designed for managing data Square One (disambiguation)