Frank McDonald may refer to:
Frank McDonald (journalist) (1950–2026), environment editor of The Irish Times Frank McDonald (director) (1899–1980), American film director Frank McDonald (footballer) (1899–1962), Australian footballer Frank B. McDonald (1925–2012), astrophysicist and creator of the Voyager probe Frank F. McDonald, former mayor of Evansville, Indiana Frank McDonald (American football) (born c. 1933), American football player Frank McDonald, Sr (1912–1997), mayor of Evansville, Indiana, 1960–1972 Frank McDonald, II (born 1951), mayor of Evansville, Indiana, 1987–2000
See also Francis McDonald (disambiguation) Franklin M. McDonald (1850–?), soldier Frank MacDonald (1896–2003), final surviving Tasmanian veteran of World War I Frankie MacDonald (born 1984), amateur weather man