Domecq is a Spanish family name. It may refer to:

Allied Domecq, a former British wine and spirits company Alcina Lubitch Domecq, a Jewish Guatemalan short story writer Álvaro Domecq y Díez, Spanish fighter pilot, bullfighting promoter and member of the Spanish sherry family Álvaro Domecq Romero, Spanish bullfighter and cattle breeder Borja Domecq Solís, Spanish businessman and breeder of fighting bulls Brianda Domecq, Spanish-Mexican novelist H. Bustos Domecq, a pseudonym used for several collaborative works by the Argentine writers Jorge Luis Borges and Adolfo Bioy Casares Jorge Domecq, Spanish diplomat Juan Domecq, Cuban basketball player , Paraguayan-Argentine admiral and politician

See also ARA Almirante Domecq Garcia (D23) Marquess of Casa Domecq