McGuire House may refer to:
Thomas R. McGuire House, Little Rock, Arkansas, NRHP-listed McGuire-Setzer House, Mocksville, North Carolina, listed on the National Register of Historic Places (NRHP) in Davie County, North Carolina McGuire House (Tulsa, Oklahoma), a work of architect John T. Blair
See also McGuires School, McGuire, Idaho, NRHP-listed McConnell-McGuire Building, Moscow, Idaho, NRHP-listed