7-Methylguanosine (m7G) is a modified purine nucleoside. It is a methylated version of guanosine and when found in human urine, it may be a biomarker of some types of cancer. In the RNAs, 7-methylguanosine have been used to study and examine the reaction evolving methylguanosine. It also participates in the formation of 5'-cap that stabilizes mRNA and prevents its degradation by 5' exonucleases.
See also m7G(5')pppN diphosphatase METTL1 Messenger RNA decapping 23S rRNA (guanine2445-N2)-methyltransferase 16S rRNA (guanine527-N7)-methyltransferase N1-Methylguanosine (m1G)
References
External links Metabocard for 7-Methylguanosine (HMDB01107), Human Metabolome Database, University of Alberta