In medicine, malaise is a feeling of general discomfort, uneasiness or lack of wellbeing and often the first sign of an infection or other disease. It is considered a vague termdescribing the state of simply not feeling well. The word has existed in French since at least the 12th century.
The term is often used figuratively in other contexts, in addition to its meaning as a general state of angst or melancholia.
Cause Malaise is a non-specific symptom and can be present in the slightest ailment, such as an emotion (e.g., causing fainting, a vasovagal response) or hunger (e.g., light hypoglycemia), to more serious conditions (e.g., cancer, stroke, heart attack, internal bleeding).
Malaise expresses a patient's uneasiness that "something is not right" that may need a medical examination to determine the significance.
Malaise is thought to be caused by the activation of an immune response, and the associated pro-inflammatory cytokines.
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