SPRM may refer to:
Science Sprm1, a POU domain protein also known as POU5F2 Selective progesterone receptor modulator Surface plasmon resonance microscopy
Other Malaysian Anti-Corruption Commission (Suruhanjaya Pencegahan Rasuah Malaysia) Somali People's Resistance Movement (Al-Shabaab) Capitán FAP Leonardo Alvariño Herr Airport (IATA code)