Frederick or Fred Hughes may refer to:
Frederick Hughes (1816–1889) of the Hughes baronets Frederick Hughes (footballer) (1860–?), Welsh footballer Frederick Hughes (sailor) (1866–1956), British Olympic sailor Frederick Llewelyn Hughes (1894–1967), Anglican priest and British Army chaplain Frederick W. Hughes (1943–2001), manager and executor of Andy Warhol Fred Hughes (rugby), 1940s Welsh rugby league footballer Fred Hughes (singer), 1960s American R&B singer Freddie Hughes (1943–2022), American gospel, soul, and R&B singer Fred G. Hughes (1837–1911), American miner, gambler, and politician Fred G. Hughes (newspaper publisher) (1915–1996), American newspaper publisher and FBI agent F. W. Hughes (Fred William Hughes, 1869–1950), Australian businessman
See also Frederic Hughes (1858–1944), Australian World War I general