Samuel Sandys, 1st Baron Sandys (1695–1770) was a British politician who served as Chancellor of the Exchequer.

Samuel Sandys may also refer to: Samuel Sandys (died 1623) (1560–1623), English landowner and politician Samuel Sandys (Royalist) (1615–1685), English politician, grandson of the above Samuel Sandys (died 1701) (–1701), English politician, son of the above, grandfather of the 1st Baron Sandys

See also Sandys (surname)