Culhuacan or Culhuacán may refer to:
Colhuacan (altepetl), a pre-Columbian city-state of the Valley of Mexico Pueblo Culhuacán, a neighborhood of the Iztapalapa borough of modern Mexico City Culhuacán metro station, a Mexico City Metro station
See also Acolhuacan, a pre-Columbian province in the east of the Valley of Mexico