The Twiste () is a river of Hesse and of North Rhine-Westphalia, Germany. It is the most important tributary of the Diemel, which it joins in Warburg. Its largest tributaries are the Erpe, Watter, Aar and Wande.

The Twistesee reservoir, in the county of Waldeck-Frankenberg in North Hesse, impounds the Twiste.

See also List of rivers of Hesse List of rivers of North Rhine-Westphalia

References