Eyles is a surname. Notable people with the surname include:
Derek Charles Eyles (1902–1974), British illustrator Don Eyles (1944), retired computer engineer, worked on the computer systems in the Apollo 11 Lunar Landing Francis Eyles (disambiguation), multiple people Frederick Eyles (1864–1937), English-born Rhodesian botanist, politician and journalist John Eyles (disambiguation), multiple people Leonora Eyles (1889–1960), novelist, memoirist and feminist Nick Eyles, University of Toronto professor Thomas Eyles (c. 1769–1835), Royal Navy officer
See also Eyles-Stiles Baronets