Yesayan may refer to:
Ashot Yesayan (born 1951), Armenian politician Bagrat Yesayan (born 1965), Armenian journalist and scout administrator Elen Yesayan (born 2003), Armenian swimmer Nune Yesayan (born 1969), Armenian pop singer Oleg Yesayan (born 1946), Armenian politician and diplomat Ruben Yesayan (1946–2026), Russian-Armenian test pilot Tigran Yesayan (born 1972), Armenian football player Zabel Yesayan (1878–1943), Armenian novelist, poet, writer, and teacher