Samuel or Sam Cunningham may refer to:
Politics Samuel Cunningham (Canadian politician) (1848–1919), member of the Northwest Territories Legislative Assembly Samuel Cunningham (Northern Ireland politician) (1862–1946), Northern Irish businessman and politician Sir Knox Cunningham (Samuel Knox Cunningham, 1909–1976), Northern Irish barrister, businessman and politician, son of the above Sam Cunningham (mayor) (fl. 1975–2017), American politician, mayor of Waukegan, Illinois
Sports Sam Cunningham (1950–2021), American football player Samuel Cunningham (footballer) (born 1989), Thai footballer
See also Samuel Cunningham House, an historic home located near Hedgesville, Berkeley County, West Virginia, United States