Acxocueitl was the first Queen consort of city-state of Tlatelolco.

She was a daughter of Acolmiztli and the princess, Tlazozomizqui.Anales de Tlatelolco She married Quaquapitzahuac.

Their children were: Tlacateotl Matlalatzin Huacaltzintli

She was a grandmother of the prince Tezozomoc and sister of Xiuhtomiyauhtzin.

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