This is a list of opioids, opioid antagonists and inverse agonists.
Opium and poppy straw derivatives
Crude opiate extracts whole opium products
B&O Supprettes Diascordium Dover's powder Kendal Black Drop Laudanum Mithridate Opium Polish heroin (Compote, Kompot) Paregoric Poppy straw concentrate Poppy tea Smoking opium Theriac
Natural opiates
Opium alkaloids
Codeine Morphine Oripavine Pseudomorphine Thebaine
Morphides Codeine Morphine Oripavine Pseudomorphine Thebaine
Alkaloid salts mixtures
Pantopon Papaveretum (Omnopon) Tetrapon
Semisynthetics including Bentley compounds
Morphine family
14-Hydroxymorphine ChemIndex CAS Registry Number 3371-56-0 2,4-Dinitrophenylmorphine 6-Methyldihydromorphine ChemIndex CAS Registry Number 509-56-8 6-Methylenedihydrodesoxymorphine 6-Acetyldihydromorphine ChemIndex CAS Registry Number 63715-94-6 Azidomorphine Chlornaltrexamine Chloroxymorphamine NCBI PubChem SID 750205 Desomorphine (dihydrodesoxymorphine) Dihydromorphine Ethyldihydromorphine chembase cbid_346222 Hydromorphinol Methyldesorphine Morphine methylbromide N-Phenethylnordesomorphine N-Phenethyl-14-ethoxymetopon N-Phenethylnormorphine 6-Nicotinoyldihydromorphine (metabolite of nicodicodeine) RAM-378 Ro4-1539
Morphine family Azidomorphine Chlornaltrexamine Chloroxymorphamine Dihydromorphine Ethyldihydromorphine Hydromorphinol Methyldesorphine RAM-378
3,6-diesters of morphine
Acetylpropionylmorphine 3,6-Dibutanoylmorphine Diacetyldihydromorphine (dihydroheroin, acetylmorphinol) Dibutyrylmorphine Dibenzoylmorphine (first designer drug) Diformylmorphine Dipropanoylmorphine Heroin (diacetylmorphine) Nicomorphine
3,6-diesters of morphine Acetylpropionylmorphine3,6-Dibutanoylmorphine Dibutyrylmorphine Dibenzoylmorphine Diformylmorphine Dipropanoylmorphine Nicomorphine
Codeine-dionine family
6-Monoacetylcodeine Benzylmorphine Codeine methylbromide Desocodeine Dimethylmorphine (6-O-Methylcodeine) Ethyldihydromorphine Methyldihydromorphine (dihydroheterocodeine) Ethylmorphine (dionine) Heterocodeine Isocodeine Pholcodine (morpholinylethylmorphine) Myrophine Thebacon Transisocodeine
Codeine-dionine family Benzylmorphine Desocodeine Dimethylmorphine(6-O-Methylcodeine) Ethyldihydromorphine Methyldihydromorphine(dihydroheterocodeine) Heterocodeine Isocodeine Pholcodine Myrophine Transisocodeine
Morphinones and morphols
14-Cinnamoyloxycodeinone 14-Ethoxymetopon 14-Methoxymetopon 14-Phenylpropoxymetopon 3-Acetyloxymorphone 3,14-Diacetyloxymorphone 7-Spiroindanyloxymorphone 8,14-Dihydroxydihydromorphinone Acetylcodone Acetylmorphone α-hydrocodol (=dihydrocodeine, ) Benzhydrocodone Bromoisopropropyldihydromorphinone cas? Codeinone Codoxime Conorfone (codorphone) IBNtxA Thebacon (acetyldihydrocodeinone, dihydrocodeinone enol acetate) Hydrocodone Hydromorphone Hydroxycodeine Metopon (=methyldihydromorphinone) Morphenol Morphinone Morphol N-Phenethyl-14-ethoxymetopon Noroxymorphone Oxycodone Oxymorphol Oxymorphone Pentamorphone Semorphone 14-Hydroxycodeine
Morphinones and morphols 14-Cinnamoyloxycodeinone 14-Ethoxymetopon 14-Methoxymetopon 14-Phenylpropoxymetopon 7-Spiroindanyloxymorphone 8,14-Dihydroxydihydromorphinone Acetylcodone Acetylmorphone α-hydrocodol(Dihydrocodeine) Bromoisopropropyldihydromorphinone Codeinone Codorphone Codol(Codeine Phosphate) Codoxime IBNtxA Thebacon Hydrocodone Hydromorphone Hydroxycodeine Morphenol Morphinone Morphol N-Phenethyl-14-ethoxymetopon Oxycodone Oxymorphol Oxymorphone Pentamorphone Semorphone
Morphides
α-Chlorocodide (= chlorocodide) β-Chlorocodide α-Chloromorphide (= chloromorphide) Bromocodide Bromomorphide Chlorodihydrocodide Chloromorphide Codide
Morphides α-chlorocodide β-chlorocodide Bromomorphide Chlorodihydrocodide. Chloromorphide Codide
Dihydrocodeine series
14-Hydroxydihydrocodeine Acetyldihydrocodeine Dihydrocodeine Dihydrodesoxycodeine (desocodeine) Dihydroisocodeine Nicocodeine Nicodicodeine
Morphides 14-Hydroxydihydrocodeine Acetyldihydrocodeine Dihydrocodeine Dihydrodesoxycodeine Dihydroisocodeine Nicocodeine Nicodicodeine
Nitrogen morphine derivatives
1-Nitrocodeine cas? Codeine-N-oxide Morphine-N-oxide
Morphides 1-Nitrocodeine Codeine-N-oxide Morphine-N-oxide
Hydrazones
Oxymorphazone
Hydrazones Oxymorphazone
Halogenated morphine derivatives
1-Bromocodeine 1-Chlorocodeine 1-Iodomorphine
Other open chain opioids 1-Bromocodeine 1-Chlorocodeine 1-Iodomorphine
Active opiate metabolites
Codeine-6-glucuronide Codeine-N-oxide (genocodeine) Heroin-7,8-oxide Morphine-6-glucuronide 3-Monoacetylmorphine 6-Monoacetylmorphine Morphine-N-oxide (genomorphine) Naltrexol Norcodeine Normorphine
Active opiate metabolites Naltrexol Norcodeine Normorphine
Morphinans
Morphinan series
3-Hydroxymorphinan 4-Chlorophenylpyridomorphinan Cyclorphan Levargorphan Levorphanol Levophenacylmorphan Levomethorphan Methorphan (racemethorphan) Morphanol (racemorphanol) Norlevorphanol N-Methylmorphinan Oxilorphan Phenomorphan Proxorphan Ro4-1539 Stephodeline Xorphanol
Other morphinans 4-chlorophenylpyridomorphinan Cyclorphan Dextrallorphan Levargorphan Levophenacylmorphan Levomethorphan Norlevorphanol N-Methylmorphinan Oxilorphan Phenomorphan Dextromethorphan levomethorphan Morphanol Ro4-1539 Stephodeline Xorphanol
Others
1-Nitroaknadinine * 14-episinomenine 5,6-Dihydronorsalutaridine 6-Keto Nalbuphine Aknadinine Butorphanol Cephakicine Cephasamine Cyprodime Drotebanol Fenfangjine G Ketorfanol Nalbuphine Nalbuphone Tannagine
Other Morphinans 1-Nitroaknadinine 14-episinomenine 5,6-Dihydronorsalutaridine 6-Keto Nalbuphine Aknadinine Butorphanol Cephakicine Cephasamine Cyprodime Drotebanol Fenfangjine G Nalbuphine Sinococuline Sinomenine Tannagine
Benzomorphans
5,9 alpha-diethyl-2-hydroxybenzomorphan (5,9-DEHB) 8-Carboxamidocyclazocine (8-CAC) Alazocine Anazocine Bremazocine Butinazocine Carbazocine Cogazocine Cyclazocine Dezocine Eptazocine Etazocine Ethylketazocine Fedotozine Fluorophen Gemazocine Ibazocine Ketazocine Metazocine Moxazocine Pentazocine Phenazocine Quadazocine SKF-10047 Tonazocine Volazocine Zenazocine
Benzomorphans 8-Carboxamidocyclazocine Alazocine Anazocine Bremazocine Butinazocine Carbazocine Cogazocine Cyclazocine Dezocine Eptazocine Etazocine Ethylketocyclazocine Fedotozine Fluorophen Gemazocine Ibazocine Ketazocine Metazocine Moxazocine Pentazocine Phenazocine Quadazocine Tonazocine Volazocine Zenazocine
4-Phenylpiperidines
Pethidines (meperidines)
4-Fluoropethidine Allylnorpethidine Anileridine Benzethidine Carperidine Difenoxin Diphenoxylate Etoxeridine (carbetidine) Furethidine Hydroxypethidine (bemidone) Morpheridine Meperidine-N-oxide Oxpheneridine (carbamethidine) Pethidine (meperidine) Pethidine intermediate A Pethidine intermediate B (norpethidine) Pethidine intermediate C (pethidinic acid) Pheneridine Phenoperidine Piminodine Properidine (ipropethidine) Sameridine
Pethidines (meperidines) 8-Carboxamidocyclazocine Allylnorpethidine Anileridine Benzethidine Carperidine Difenoxin Diphenoxylate Etoxeridine Furethidine Hydroxypethidine Morpheridine Meperidine-N-oxide Oxpheneridine Pethidine Pethidine intermediate A Pethidine intermediate B Pethidine intermediate C Pheneridine Phenoperidine Piminodine Sameridine
Prodines
Allylprodine (α/β)-Meprodine Desmethylprodine (MPPP) PEPAP (α/β)-Prodine Prosidol Trimeperidine (promedol)
Prodines (α/β)-Meprodine Desmethylprodine (MPPP) PEPAP Prodine Prosidol Prosidol
Ketobemidones
Acetoxyketobemidone Droxypropine Ketobemidone Methylketobemidone Propylketobemidone
Ketobemidones Droxypropine Ketobemidone Methylketobemidone Propylketobemidone
Others
Alvimopan Loperamide LS-115509 Picenadol
Other phenylpiperidines Loperamide LS-115509 Picenadol
Open chain opioids
Amidones
Dextromethadone Dipipanone Dipyanone Isomethadone Levoisomethadone Levomethadone Methadone Methadone intermediate Normethadone Norpipanone Phenadoxone (heptazone)
Amidones Dextromethadone Dipipanone Isomethadone Levoisomethadone Noracetylmethadol Levomethadone Methadone Normethadone Norpipanone Phenadoxone Pipidone
Methadols
Acetylmethadol Alphaacetylmethadol Alphamethadol Betacetylmethadol Betamethadol Dimepheptanol (racemethadol) Isomethadol Levacetylmethadol Noracymethadol
Other open chain opioids Alphaacetylmethadol Dimepheptanol Levacetylmethadol Noracetylmethadol
Moramides
Desmethylmoramide Dextromoramide Levomoramide Moramide intermediate Racemoramide
Other open chain opioids Desmethylmoramide Dextromoramide Levomoramide Moramide intermediate Racemoramide
Thiambutenes
Diethylthiambutene Dimethylthiambutene Ethylmethylthiambutene Piperidylthiambutene Pyrrolidinylthiambutene Thiambutene
Thiambutenes Diethylthiambutene Dimethylthiambutene Ethylmethylthiambutene Piperidylthiambutene Thiambutene Tipepidine
Phenalkoxams
Dextropropoxyphene (propoxyphene) Dimenoxadol Dioxaphetyl butyrate Levopropoxyphene Norpropoxyphene Pyrroliphene
Phenalkoxams Dextropropoxyphene (propoxyphene) Dimenoxadol Dioxaphetyl butyrate Levopropoxyphene Norpropoxyphene
Ampromides
Diampromide Phenampromide Propiram
Ampromides Diampromide Phenampromide Propiram
Others
Embutramide IC-26 Isoaminile Lefetamine R-4066
Other open chain opioids Embutramide IC-26 Isoaminile Lefetamine R-4066
Anilidopiperidines
3-Allylfentanyl 3-Methylfentanyl 3-Methylthiofentanyl 4-Phenylfentanyl Alfentanil α-Methylacetylfentanyl α-Methylfentanyl α-Methylthiofentanyl Benzylfentanyl β-hydroxyfentanyl β-hydroxythiofentanyl β-Methylfentanyl Brifentanil Butyrfentanyl Carfentanil Fentanyl Lofentanil N-Methylcarfentanil Mirfentanil Ocfentanil Ohmefentanyl Parafluorofentanyl Phenaridine R-30490 Remifentanil Sufentanil Thenylfentanyl
Thiofentanyl Trefentanil
Anilidopiperidines Alfentanil Alphamethylacetylfentanyl Alphamethylfentanyl Alpha-methylthiofentanyl Benzylfentanyl Betahydroxyfentanyl Betahydroxythiofentanyl Betamethylfentanyl Brifentanil Carfentanil Fentanyl Lofentanil Mirfentanil Ocfentanil Ohmefentanyl Parafluorofentanyl Phenaridine Remifentanil Sufentanil Thenylfentanyl Thiofentanyl Trefentanil
Oripavine derivatives
7-PET Acetorphine Alletorphine (N-allyl-noretorphine) BU-48 Buprenorphine Buprenorphine-3-glucuronide Cyprenorphine Dihydroetorphine Etorphine Homprenorphine 18,19-Dehydrobuprenorphine (HS-599) N-cyclopropylmethylnoretorphine Nepenthone Norbuprenorphine Norbuprenorphine-3-glucuronide Thevinone Thienorphine TH-030418
Oripavine derivatives 7-PET Acetorphine Alletorphine BU-48 Buprenorphine Cyprenorphine Dihydroetorphine Etorphine Homprenorphine Nepenthone Norbuprenorphine Thevinone Thienorphine
Phenazepanes
Ethoheptazine Meptazinol Metheptazine Metethoheptazine Proheptazine
Phenazepanes Ethoheptazine Meptazinol Metheptazine Metethoheptazine Proheptazine
Pirinitramides
Bezitramide Piritramide
Pirinitramides Bezitramide Piritramide
Benzimidazoles
Clonitazene Etonitazene Isotonitazene Metonitazene
Benzimidazoles Clonitazene Etonitazene Isotonitazene Metonitazene Nitazene: R = hydrogen
Indoles
18-Methoxycoronaridine 7-Acetoxymitragynine 7-Hydroxymitragynine ψ-Akuammigine Akuammidine Akuammine Coronaridine Eseroline Hodgkinsine Ibogaine Mitragynine Mitragynine pseudoindoxyl MGM-15 Noribogaine Pericine Pseudoakuammigine
Indoles 18-Methoxycoronaridine 7-Acetoxymitragynine 7-Hydroxymitragynine Akuammidine Akuammine Eseroline Hodgkinsine Mitragynine Pericine Pseudoakuammigine
Beta-Amino Ketones
3-(dimethylamino)-2,2-dimethyl-1-phenylpropan-1-one
Indoles3-(dimethylamino)-2,2-dimethyl-1-phenylpropan-1-one (Beta-amine ketone 'compound 29')