Boothby is a surname. Notable people with the surname include:

Basil Boothby (1910–1990), British diplomat Benjamin Boothby (1803–1868), judge of the Supreme Court of South Australia Sir Brooke Boothby, 6th Baronet (1744–1824), British poet and friend of Jean-Jacques Rousseau Sir Brooke Boothby, 10th Baronet (1856–1913), British diplomat David Boothby (born 1944), Canadian Police Chief Dora Boothby (1881–1970), English tennis player Frances Boothby (fl. 1669–1670), English playwright Frederic E. Boothby (1845–1923), American railroad manager and politician Guy Boothby (1867–1905), Australian-born author of the Dr. Nikola novels Ian Boothby (born 1967), comic book writer, comedian Josiah Boothby (1837–1916), Australian public administrator Neil Boothby, child psychologist Robert Boothby, Baron Boothby (1900–1986), British politician Robert Tuite Boothby (1871–1941), British banker, father of Robert Boothby Scott Boothby (born 1973), American hammer thrower Thomas Boothby of Tooley, founder of the Quorn Hunt in Leicestershire, England Thomas Wilde Boothby (1839–1885), aka T. Wilde Boothby, a politician in South Australia Valerie Boothby (1906–1982), German actress William Boothby (1829–1903), the Returning Officer for the first Australian federal election, after whom the Division of Boothby was named William "Cocktail" Boothby (1862–1930), bartender, mixologist, author of The World's Drinks And How To Mix Them William M. Boothby (1918–2021), American mathematician