Valentine Blake (1560–1635) was an Irish merchant and Mayor of Galway.

Valentine Blake may also refer to:

Sir Valentine Blake, 3rd Baronet (died 1652) Sir Valentine Blake, 5th Baronet (died c. 1672), of the Blake baronets Sir Valentine Blake, 12th Baronet (1780-1847), MP for Galway Borough, of the Blake baronets Sir Valentine Blake, 14th Baronet (1836–1912), of the Blake baronets

See also Blake (surname)