Flight 1 or Flight 001 may refer to one of the following airline incidents, listed chronologically:
American Airlines Flight 1 (1936), a Douglas DC-2 that crashed near Goodwin, Arkansas, on 14 January 1936 TWA Flight 1, a Douglas DC-2 that crashed in Pennsylvania on 7 April 1936 Northwest Airlines Flight 1, a Lockheed Super Electra that suffered a fire on board and crashed in Montana on 13 January 1939 American Airlines Flight 1 (1941), a Douglas DC-3 that crashed near Lawrence Station, Ontario, on 30 October 1941 Transair Sweden Flight 001, crashed near Ndola, Northern Rhodesia (present-day Zambia), on 18 September 1961 American Airlines Flight 1 (1962), a Boeing 707 that crashed after a rudder failure just out of New York on 1 March 1962 ČSA Flight 001, crashed in Czechoslovakia on 28 July 1976 Loftleiðir Flight 001, crashed on approach to Colombo, Sri Lanka, on 15 November 1978 Qantas Flight 1, a Boeing 747 that overran a runway in Bangkok on 23 September 1999 Zeusch Aviation Flight 1, a Beechcraft Super King Air that crashed after takeoff at London Southend Airport on 13 July 2025
Other uses "Flight 1" (Mad Men), a 2008 episode of the television show Mad Men, centering in part on the above noted 1962 American Airlines crash SpaceX COTS Demo Flight 1, a test flight on 8 December 2010 Starship flight test 1, the unsuccessful maiden flight of SpaceX Starship and Super Heavy on April 20, 2023
See also List of flight number 1 by airline