Sise is a surname. Notable people with the surname include:
Charles Fleetford Sise, Sr, Canadian businessman Charles Fleetford Sise Jr, Canadian businessman Edward Fleetford Sise, Canadian businessman Gage Sise, Officer in the Royal New Zealand Air Force Hazen Sise, Canadian architect, educator, and humanitarian Joe Sise (born 1989), Swedish footballer Paul Fleetford Sise, Canadian businessman
See also Si*Sé, an electronic music group from the US Sisse, a Danish female given name Size (disambiguation)