Cathedral of Our Lady of Perpetual Help may refer to:
Cathedral of Our Lady of Perpetual Help (Rapid City, South Dakota), US Cathedral of Our Lady of Perpetual Help (Oklahoma City), US Cathedral of Our Lady of Perpetual Succour (Prizren), Kosovo Our Lady of Perpetual Help Cathedral, El Vigia, Venezuela Our Lady of Perpetual Help Cathedral, Niamey, Niger Kidane Mehret Cathedral, Asmara, Eritrea Pro-Cathedral of Our Lady of Perpetual Help, San Fernando, Trinidad
See also Our Mother of Perpetual Help Cathedral, Astana, Kazakhstan Our Lady of Perpetual Help Church (disambiguation)