Calfee may refer to:
Carolyn Calfee (born 1974), American intensive care physician Jack Calfee (1941–2011), American economist and author Kent Calfee (born 1949), American politician Robert C. Calfee (1933–2014), American educational psychologist
Calfee Design, California designer and manufacturer of carbon fiber bicycle frames by Craig Calfee Calfee Park, a stadium in Pulaski, Virginia, used primarily for baseball Calfee Nunatak, a geographical feature in Antarctica