Klippel is a German surname. Notable people with the surname include:
Maurice Klippel (1858–1942), French physician Klippel–Feil syndrome Klippel–Trénaunay–Weber syndrome Robert Klippel (1920–2001), Australian constructivist sculptor and teacher Heike Klippel (born 1960), German film and media studies scholar Christoph Klippel (born 1986), German footballer