Otterson is a surname. Notable people with the surname include:
Billy Otterson (1862–1940), American baseball player Jack Otterson (1905–1991), American art director Joel Otterson (born 1959), American artist John E. Otterson (1881–1964), American engineer and business executive Michael Otterson, managing director of Public Affairs for The Church of Jesus Christ of Latter-day Saints Ryan Otterson (born 1986), American football offensive tackle Suzanne Otterson (born 1974), British figure skater