Gainsford is a surname. The usual medieval spelling was Gaynesford. Notable people with the surname include:
Anne Gainsford (died c. 1590), lady-in-waiting to Anne Boleyn Ian Gainsford (born 1930), British academic John Gainsford (1938–2015), South African rugby union player Melinda Gainsford-Taylor (born 1971), Australian athlete Nicholas Gaynesford (c. 1427–1498), British politician Thomas Gainsford (died 1624), British author and editor
Other uses Gainsford End, a hamlet in Toppesfield, England Gainsford, Queensland, a locality in the Central Highlands Region, Australia