The year 1549 in science and technology included some events, a few of which are listed here.

Births November 30 – Henry Savile, English polymath and benefactor (died 1622) Michiel Coignet, Flemish engineer, cosmographer, mathematician and scientific instrument-maker (died 1623) Nikola Vitov Gučetić, Ragusan polymath (died 1610)

Deaths April – Andrew Boorde, English physician and traveller (born 1490) August – Jacob Ziegler, German geographer (born c. 1470/1)

References