A biphasic disease is a disease which has two distinct phases or components. In clinically biphasic diseases, the phases are generally chronologically separated. In histopathologically biphasic tumors (also called biplastic tumors), there is neoplastic tissue which contains two different cellular elements.
Examples of a biphasic desease Clinically biphasic diseases Disease Typical first phase Typical second phase European (or "Western") subtype of tick-borne encephalitis virus Relatively mild flu-like illness Affecting some cases, generally presenting with high fever and neurologic disease (encephalitis), meningitis and/or meningoencephalitis) Leptospirosis Page last updated 26 Jun 2017 4–9 days of abrupt onset of flu-like illness Fever, jaundice, abdominal pain and diarrhoea. Organ failure in severe cases. Anthrax After approximately 4 days, patients develop flu-like illness with fever, nonproductive cough, and myalgias lasting approximately 4 days Without timely treatment, a second fulminant phase follows, characterized by hypotension and dyspnea. This phase may progress to death within 24 hours of its onset.
Tumor biplasia
Disease Cellular elements Fibroadenoma Epithelium Stroma Ceruminous adenoma Inner luminal secretory cells Myoepithelial cells
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