Mother of Cities may refer to: Mecca, is the capital of Mecca Province in western Saudi Arabia, the holiest city in Islam, and is referenced in the Quran as the 'mother of cities'. See Quran 6:92, 42:7. Asunción, capital and largest city of Paraguay. Balkh, among the oldest cities of Afghanistan. Prague, capital and largest city of the Czech Republic. Santiago del Estero, oldest city of Argentina.
See also Mother city (disambiguation) Queen City (disambiguation)