Duprey is a surname. Notable people with the surname include:
Ana Roque de Duprey (1853–1933), educator, suffragist and one of the founders of the University of Puerto Rico Brian Duprey (born 1967), former Maine State Representative from Hampden Cyril Duprey (1897–1988), Trinidad and Tobago businessman Donalda Duprey (born 1967), Canadian athlete Janet Duprey (born 1945), Republican member of the New York State Assembly Jean-Pierre Duprey (1930–1959), French poet and sculptor Louise Duprey (1957–2000), British character actress Maurice Duprey, politician in Manitoba, Canada Phil Duprey (1944–2015), American bobsledder Rob Duprey, American rock musician