Alco typically refers to the American Locomotive Company, a defunct locomotive manufacturer.

Alco may also refer to:

Companies ALCO Stores, a defunct American discount store Alco Hydro-Aeroplane Company, the original name of the company that became Lockheed Corporation ALCO was a trade name of the British company Arthur Lyon & Co of London

Places Alco, Arkansas, an unincorporated community in Stone County Alco, Louisiana, an unincorporated community in Vernon Parish Alco, Texas, a ghost town in Angelina County

Other uses Alcon (classical history), an Ancient Greek name whose Latin form Alco is also used in English Acción Cultural Loyola (ACLO), a Bolivian radio network ALCO, the Asset and liability management committee

See also Alko, the national alcoholic beverage retailing monopoly in Finland