Sayuki is a feminine Japanese given name. Notable people with the name include:
Fiona Graham (1961–2023), an Australian anthropologist and professional geisha named Sayuki Sayuki Takagi (born 1997), a Japanese pop singer
Fictional characters Sayuki Ayase, a character in the Your Diary visual novel Sayuki Katagiri, a character in the light novel and anime series Lovely Idol Sayuki Kuroda, a character in the visual novel Girls Beyond the Wasteland Sayuki Manaka, a character in the media series Duel Masters Sayuki Sakurai, a character in the manga series Chocolate Cosmos Sayuki Shirakawa, a character in the visual novel series A Kiss for the Petals Sayuki Takigawa, a character in the 22/7 anime TV series Sayuki Tezuka, a character in the game and anime series Night Shift Nurses Sayuki Tokihara, a character in the light novel series Hensuki
See also Heavenly Guardian, a 2007 video game known as Legend of Sayuki in Europe