Francillon is a surname, and may refer to:

Ernest Francillon (1834–1900), founder and manager of Longines watch manufacturing company Henri Françillon (born 1946), Haitian footballer James Francillon (1802–1866), English barrister and legal writer John Francillon (1744–1816), English jeweller and naturalist Robert Edward Francillon (1841–1919), English journalist and author

See also Francillon, Indre, France Francillon-sur-Roubion, Drôme, France Francillon was also the title of Alexandre Dumas, fils's last play.