N-Phenethylnordesomorphine is an opiate analgesic drug derived from desomorphine by replacing the N-methyl group with β-phenethyl. Since desomorphine is already around eight times more potent than morphine, the additional boost in binding affinity produced by using the larger phenethyl group makes N-phenethylnordesomorphine a highly potent analgesic drug, some 85 times more potent than morphine, and a similar strength to the closely related morphinan derivative phenomorphan.
See also 14-Cinnamoyloxycodeinone 14-Phenylpropoxymetopon 7-PET N-Phenethyl-14-ethoxymetopon N-Phenethylnormorphine N-Phenethylnoroxymorphone RAM-378 Ro4-1539
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