Brian Mayes may refer to:
Brian Mayes (British Army officer) (1934–2019), British general in the Royal Army Medical Corps Brian Mayes (cricketer) (born 1950), English cricketer Brian Mayes, Winnipeg City Councillor first elected in 2010, see Winnipeg City Council
See also Brian May (born 1947), British musician Brian May (Australian composer) (1934–1997)