Mazzetti is an Italian surname.
List of people with the surname Mazzetti Annamaria Mazzetti (born 1988), an Italian triathlete Cocky Mazzetti (1937–2024), an Italian singer Germana Mazzetti (1931–2024), birth name of Italian singer Germana Caroli Mark Mazzetti (born 1974), an American journalist with The New York Times Pilar Mazzetti (born 1956), a Peruvian doctor and Minister of the Interior Tim Mazzetti (born 1956), a former National Football League placekicker