Web of Evil is a publication of Quality Comics,The Classic Era of American Comics, Nicky Wright, Contemporary Books, 2000, Pg. 178. which began in November 1952. The comic had a run of twenty-one issues.,Web of Evil, Comic Values Annual 1999, Antique Trader Books, 1998, Pg. 431. the final issue being #21 (December 1954).Overstreet Comic Book Price Guide, Gemstone Publishing, May 2002, Pg. 837. Comics historian Nicky Wright has described Web of Evil as an inferior imitation of Exciting Comics' style horror comics.

The final comic book work of artist Jack Cole was in Web of Evil.Jack Cole and Plastic Man: forms stretched to their limits, Art Spiegelman and Chip Kidd, Chronicle Books, 2001, Pg. 93. Web of Evil themes include #1 (morphine use), #5 (electrocution), #14 (old witch swipe), #17 (opium drug propaganda), and #18 (acid-in-face story).

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