Ziskind is a Jewish Ashkenazi surname meaning sweet child. Notable people with the surname include:
Alexander Ziskind Maimon (1809–1887), Lithuanian rabbi Haim Ziskind (born 1990), Israeli footballer Tamar Ziskind (born 1985), Israeli beauty pageant contestant Trudi Ziskind (born 1946), known professionally as Trudi Ames, American actor
See also Ziskin Susskind