Swanepoel is an Afrikaans surname, derived from the Dutch Zwaenepoel. Notable people with the surname include:
Candice Swanepoel, South African supermodel Chris Swanepoel, South African golfer Corney Swanepoel, New Zealand swimmer Landi Swanepoel, South African model Pieter Swanepoel, South African cricketer Stephan Swanepoel, Namibian cricketer Tiaan Swanepoel, Namibian rugby union player Werner Swanepoel, South African rugby player
See also Swanepoelspoort - a mountain pass in South Africa