Lucrezia d'Este may refer to:
(born ), daughter of Ercole I d'Este, Duke of Ferrara, married Annibale II Bentivoglio (1467–1540) Lucrezia d'Este (daughter of Sigismondo) (before 1490 – after 1505), see Sigismondo d'Este (1433–1507) and Malaspina family Lucrezia d'Este (1535–1598), daughter of Ercole II d'Este, Duke of Ferrara